Unani medicine first arrived in India around 12th or 13th century with establishment of Delhi Sultanate (1206-1527) and Islamic rule over North India and subsequently flourished under Mughal Empire. Alauddin Khilji (r. 1296-1316) had several eminent Unani physicians (Hakims) in his royal courts In the coming year this royal patronage meant development of Unani practice in India, but also of Unani literature with the aid of Indian Ayurvedic physicians.
Unani classical literature consists of thousands of books and contains vast knowledge and mention of experiences on all aspects of medicine. According to Unani medicine, management of any disease depends upon the diagnosis of disease. In the diagnosis, clinical features, i.e., signs, symptoms, laboratory features and mizaj (temperament) are important.
Any cause and or factor is countered by Quwwat-e-Mudabbira-e-Badan (the power of body responsible to maintain health), the failing of which may lead to quantitatively or qualitatively derangement of the normal equilibrium of akhlat (humors) of body which constitute the tissues and organs. This abnormal humor leads to pathological changes in the tissues anatomically and physiologically at the affected site and exhibits the clinical manifestations.